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How mRNA went from a scientific backwater to a pandemic crusher

How mRNA went from a scientific backwater to a pandemic crusher

TRIAL OFFERPrint + digital, only £19 for a yearLoading...0/0Welcome to WIRED UK. This site uses cookies to improve your experience and deliver personalised advertising. You can at any time or find out more by reading our .In 1995, Katalin Karikó was at her lowest ebb. A biochemist at the University of Pennsylvania (UPenn), Karikó had dedicated much of the previous two decades to finding a way to turn one of the most fundamental building blocks of life, mRNA, into a whole new category of therapeutics.More often than not, Karikó found herself hitting dead ends. Numerous grant applications...

February 5, 2020
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Does the key to anti-ageing lie in our bones?

Does the key to anti-ageing lie in our bones?

érard Karsenty was a young scientist trying to make a name for himself in the early 1990s when he first stumbled upon a finding that would go on to transform our understanding of bone, and the role it plays in our body.Karsenty had become interested in osteocalcin, one of the most abundant proteins in bone. He suspected that it played a crucial role in bone remodelling – the process by which our bones continuously remove and create new tissue – which enables us to grow during childhood and adolescence, and also recover from injuries.Intending to study this, he conducted a genetic knockout...

July 4, 2020
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Drafted by Circumstance - Shadowproof

Drafted by Circumstance - Shadowproof

Welcome to Independence Day 2014, the day we celebrate our independence through revolutionary violence from Great Britain.In CONGRESS, July 4, 1776The unanimous Declaration of the thirteen United States of America,When in the Course of human events, it becomes necessary for one people to dissolve the political bands which have connected them with another, and to assume among the powers of the earth, the separate and equal station to which the Laws of Nature and of Nature’s God entitle them, a decent respect to the opinions of mankind requires that they should declare the causes which impel...

July 9, 2014
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