On May 15, the City announced that 730 Stanyan (formerly McDonald’s) would become the in San Francisco; the first being in the . In response to this decision, neighbors in the Upper Haight and District 5 have organized, forming a new group — Safe Healthy Haight — to represent the legitimate concerns of residents regarding this site that have so far been ignored. See the bottom of this post for ways you can get involved and to sign up for our email list.While everyone agrees that homeless residents need help during these difficult times, we don’t believe Supervisor Preston’s haphazard...…On May 15, the City announced that 730 Stanyan (formerly McDonald’s) would become the in San Francisco; the first being in the . In response to this decision, neighbors in the Upper Haight and District 5 have organized, forming a new group — Safe Healthy Haight — to represent the legitimate concerns of residents regarding this site that have so far been ignored. See the bottom of this post for ways you can get involved and to sign up for our email list.While everyone agrees that homeless residents need help during these difficult times, we don’t believe Supervisor Preston’s haphazard...WW…

More well thought out work can be found at — Axial invests and partners in early-stage life sciences companies. If you or someone you know has a great idea or company in life sciences, Axial would be excited to get to know you and possibly invest in your vision and company — Vividion is led by Diego Miralles (CEO) with the founders being Benjamin Cravatt, Phil Baran, and Jin-Quan Yu. Diego is the former president of Adaptive Biotechnologies and a former Johnson & Johnson executive. Benjamin, Phil and Jin-Quan are on faculty at .Vividion focuses on discovering targeted protein degradation...…More well thought out work can be found at — Axial invests and partners in early-stage life sciences companies. If you or someone you know has a great idea or company in life sciences, Axial would be excited to get to know you and possibly invest in your vision and company — Vividion is led by Diego Miralles (CEO) with the founders being Benjamin Cravatt, Phil Baran, and Jin-Quan Yu. Diego is the former president of Adaptive Biotechnologies and a former Johnson & Johnson executive. Benjamin, Phil and Jin-Quan are on faculty at .Vividion focuses on discovering targeted protein degradation...WW…

Get these analyses to your inbox — This is a newsletter for rough-around-the-edges ideas. More well thought out work can be found at — Axial invests and partners in early-stage life sciences companies. If you or someone you know has a great idea or company in life sciences, Axial would be excited to get to know you and possibly invest in your vision and company — A weekly overview of the development of new medicines.- released phase 1a/b data for their hepatitis B RNAi medicine, AB-729:- reported phase 1 on their allogeneic cell therapy, ATA188, in progressive multiple sclerosis showing...…Get these analyses to your inbox — This is a newsletter for rough-around-the-edges ideas. More well thought out work can be found at — Axial invests and partners in early-stage life sciences companies. If you or someone you know has a great idea or company in life sciences, Axial would be excited to get to know you and possibly invest in your vision and company — A weekly overview of the development of new medicines.- released phase 1a/b data for their hepatitis B RNAi medicine, AB-729:- reported phase 1 on their allogeneic cell therapy, ATA188, in progressive multiple sclerosis showing...WW…

As kids, we dream of finding hidden treasure; the thought of stumbling across a chest filled with gold coins or jewels is the stuff of which dreams are made. Believe it or not, there have been plenty of people who came across extremely rare discoveries worth a fortune.Many of these found artifacts don’t only have a high monetary value attached to them, but a significant cultural one as well. Whether it’s an array of gold and silver found in a sunken shipwreck, or something rare buried deep in the ground, the worth of these objects below is mind-blowing!Crosby Garrett helmet ($3.6. million):...…As kids, we dream of finding hidden treasure; the thought of stumbling across a chest filled with gold coins or jewels is the stuff of which dreams are made. Believe it or not, there have been plenty of people who came across extremely rare discoveries worth a fortune.Many of these found artifacts don’t only have a high monetary value attached to them, but a significant cultural one as well. Whether it’s an array of gold and silver found in a sunken shipwreck, or something rare buried deep in the ground, the worth of these objects below is mind-blowing!Crosby Garrett helmet ($3.6. million):...WW…

Get these analyses to your inbox — This is a newsletter for rough-around-the-edges ideas. More well thought out work can be found at — Axial invests and partners in early-stage life sciences companies. If you or someone you know has a great idea or company in life sciences, Axial would be excited to get to know you and possibly invest in your vision and company — A set of ideas and observations from a week’s worth of work analyzing businesses and technologies.Targeted protein degradationProteolysis-targeting chimeras (PROTAC) and other targeted protein degradation drugs use the...…Get these analyses to your inbox — This is a newsletter for rough-around-the-edges ideas. More well thought out work can be found at — Axial invests and partners in early-stage life sciences companies. If you or someone you know has a great idea or company in life sciences, Axial would be excited to get to know you and possibly invest in your vision and company — A set of ideas and observations from a week’s worth of work analyzing businesses and technologies.Targeted protein degradationProteolysis-targeting chimeras (PROTAC) and other targeted protein degradation drugs use the...WW…

Five courts are involved, but every Texan can request a mail-in ballot to avoid risk of injuryThe right to vote is the most fundamental right in a democracy. Texas Republicans want to suppress our vote by forcing us into a terrible choice: protecting our health or participating in our elections. They are waging a war against vote-by-mail. We can’t let them win.If you’ve been following the news, you may know that five different courts have chimed in to answer the question: Who can vote by mail during a coronavirus pandemic? Without reading the decisions and understanding legal procedure, you...…Five courts are involved, but every Texan can request a mail-in ballot to avoid risk of injuryThe right to vote is the most fundamental right in a democracy. Texas Republicans want to suppress our vote by forcing us into a terrible choice: protecting our health or participating in our elections. They are waging a war against vote-by-mail. We can’t let them win.If you’ve been following the news, you may know that five different courts have chimed in to answer the question: Who can vote by mail during a coronavirus pandemic? Without reading the decisions and understanding legal procedure, you...WW…

The now famous Einstein-Szilárd letter was written at the initiative of Hungarian nuclear physicist Leó Szilárd with help from Edward Teller and Eugene Wigner in 1939. It was signed by Albert Einstein and sent to the President of the United States, Franklin D. Roosevelt in October 1939. The letter argued that the United States should engage in uranium research. Its writing was motivated by the news of the discovery of uranium fission by Otto Hahn and Fritz Strassmann nine months prior.The letter prompted Roosevelt to propose the undertaking of what would later become the Manhattan Project...…The now famous Einstein-Szilárd letter was written at the initiative of Hungarian nuclear physicist Leó Szilárd with help from Edward Teller and Eugene Wigner in 1939. It was signed by Albert Einstein and sent to the President of the United States, Franklin D. Roosevelt in October 1939. The letter argued that the United States should engage in uranium research. Its writing was motivated by the news of the discovery of uranium fission by Otto Hahn and Fritz Strassmann nine months prior.The letter prompted Roosevelt to propose the undertaking of what would later become the Manhattan Project...WW…

Primary election season in Utah means there are six candidates for lieutenant governor in the state. Media outlets in Utah have covered the gubernatorial candidates relatively extensively, but the same can’t be said about the lieutenant governor candidates, even though the lieutenant governor is responsible for elections.Below are candidates Karina Brown’s and Rep. Rob Bishop’s responses to three questions: “What is your story?,” “What would you like to do as Utah’s lieutenant governor?” and “What is your favorite film and why?”The other lieutenant governor candidates — Michelle Kaufusi,...…Primary election season in Utah means there are six candidates for lieutenant governor in the state. Media outlets in Utah have covered the gubernatorial candidates relatively extensively, but the same can’t be said about the lieutenant governor candidates, even though the lieutenant governor is responsible for elections.Below are candidates Karina Brown’s and Rep. Rob Bishop’s responses to three questions: “What is your story?,” “What would you like to do as Utah’s lieutenant governor?” and “What is your favorite film and why?”The other lieutenant governor candidates — Michelle Kaufusi,...WW…

Brave Browser & BAT ( Earn BAT tokens by using the Brave Browser )Basic Attention Token is the new token for the digital advertising industry created by founder of Javascript. It pays publishers for their content and users for their attention while providing advertisers with more in return for their ads.asic Attention Token shares 70% of their ad revenues with their users. Simply, enable “Brave Ads” within the browser and get notified about ads to earn free BAT while surfing the web. You can also earn BAT by claiming random token grants worth 25–40 BAT. New token grants typically become...…Brave Browser & BAT ( Earn BAT tokens by using the Brave Browser )Basic Attention Token is the new token for the digital advertising industry created by founder of Javascript. It pays publishers for their content and users for their attention while providing advertisers with more in return for their ads.asic Attention Token shares 70% of their ad revenues with their users. Simply, enable “Brave Ads” within the browser and get notified about ads to earn free BAT while surfing the web. You can also earn BAT by claiming random token grants worth 25–40 BAT. New token grants typically become...WW…

Can the cryptocurrency Idena ( ) be a solution for a Universal Basic Income? I tried it for a week, here’s how it went…In short, UBI means: money is given to everyone to cover basic expenses. Everybody qualifies, no hoops to jump through. And, of course, it’s up to you if you would like to supplement the income and earn more money.My story starts about 11 weeks ago. And, living from UBI was never the plan.Confidence in Idena had grown, quietly, since the start.A Universal Basic Income is just 1 of Idena’s use casesAdd corona virus + lockdown into the mix. Opportunity & curiosity collided,...…Can the cryptocurrency Idena ( ) be a solution for a Universal Basic Income? I tried it for a week, here’s how it went…In short, UBI means: money is given to everyone to cover basic expenses. Everybody qualifies, no hoops to jump through. And, of course, it’s up to you if you would like to supplement the income and earn more money.My story starts about 11 weeks ago. And, living from UBI was never the plan.Confidence in Idena had grown, quietly, since the start.A Universal Basic Income is just 1 of Idena’s use casesAdd corona virus + lockdown into the mix. Opportunity & curiosity collided,...WW…

MegaBots had a clear goal — make giant fighting robots a reality.MegaBots, Inc. was founded in 2014 by Gui Cavalcanti, Matt Oehrlein and Andrew Stroupand. The company got viral in 2015 when they challenged Suidobashi Heavy Industries from Japan for a fight — their Kuratas (the first-ever giant combat robot) vs MegaBots Mk.II. under one condition — there has to be a melee fight.The internet exploded and was waiting for the first-ever big robots fight.MegaBots got to the work.The team expanded. Grant Imahara from Mythbusters, Peter Diamandis, founder of the X-Prize, Trey Roski and Greg...…MegaBots had a clear goal — make giant fighting robots a reality.MegaBots, Inc. was founded in 2014 by Gui Cavalcanti, Matt Oehrlein and Andrew Stroupand. The company got viral in 2015 when they challenged Suidobashi Heavy Industries from Japan for a fight — their Kuratas (the first-ever giant combat robot) vs MegaBots Mk.II. under one condition — there has to be a melee fight.The internet exploded and was waiting for the first-ever big robots fight.MegaBots got to the work.The team expanded. Grant Imahara from Mythbusters, Peter Diamandis, founder of the X-Prize, Trey Roski and Greg...WW…

Defining a vision gives your team something to aim for in the longer term — something beyond quarterly goals and outcomes. Here’s how to create one with your team…I recently wrote about the importance of having a . Purpose is just one piece of the puzzle when it comes to setting your product team up for success. Your team also needs something to aim for, a North Star.A team vision is a longer term aim that looks out around 12 months ahead. It’s different from a company vision as it’s something a little more specific than a lofty 5–10 year goal. It should be something that can be achieved in...…Defining a vision gives your team something to aim for in the longer term — something beyond quarterly goals and outcomes. Here’s how to create one with your team…I recently wrote about the importance of having a . Purpose is just one piece of the puzzle when it comes to setting your product team up for success. Your team also needs something to aim for, a North Star.A team vision is a longer term aim that looks out around 12 months ahead. It’s different from a company vision as it’s something a little more specific than a lofty 5–10 year goal. It should be something that can be achieved in...WW…

UPDATED: May 14th 2020When Microsoft , with some humility, it would go ‘carbon negative’ and account for 'Scope 3' emissions (raw materials, manufacture, transport, storage, sale, use and disposal) it was met with some initial praise. in . Some .Microsoft has while . It spent years claiming to be ‘100 percent carbon neutral’ while offsetting only three percent of its emissions.In this post I’ve questioned Microsoft’s new 'carbon math’; examined misuses of the term 'carbon neutral’; built the most detailed list of fossil fuel partnerships yet reported; weighted the reputational cost; and...…UPDATED: May 14th 2020When Microsoft , with some humility, it would go ‘carbon negative’ and account for 'Scope 3' emissions (raw materials, manufacture, transport, storage, sale, use and disposal) it was met with some initial praise. in . Some .Microsoft has while . It spent years claiming to be ‘100 percent carbon neutral’ while offsetting only three percent of its emissions.In this post I’ve questioned Microsoft’s new 'carbon math’; examined misuses of the term 'carbon neutral’; built the most detailed list of fossil fuel partnerships yet reported; weighted the reputational cost; and...WW…

These are my expectations for the short and long-run.— Author: Firas GHRIBIIf you are interested in my writings or for a collaboration/opportunity or a private feedback or you want to ask me something, please don’t hesitate to contact me. : firas.ghribi@outlook.com | | | Once the virus is defeated, a new world will emerge and radical changes are there waiting to appear. So these are my 30 Predictions for the future and what to expect.Oil demand will shift negatively, whereas the demand for substitutions (green energy) will soar and hack the supply radically at a double quick pace.Fiat money...…These are my expectations for the short and long-run.— Author: Firas GHRIBIIf you are interested in my writings or for a collaboration/opportunity or a private feedback or you want to ask me something, please don’t hesitate to contact me. : firas.ghribi@outlook.com | | | Once the virus is defeated, a new world will emerge and radical changes are there waiting to appear. So these are my 30 Predictions for the future and what to expect.Oil demand will shift negatively, whereas the demand for substitutions (green energy) will soar and hack the supply radically at a double quick pace.Fiat money...WW…

Why it is necessary and usefulThe insurance industry is a huge market. In the United States, in 2019, the volume of paid insurance premiums amounted to a trillion dollars. However, despite such volumes, the industry is experiencing great difficulties, because of which insurance companies are losing more than $100 billion every year. Most of the problems are fraud, poor-quality data or lack thereof, as well as the general inefficiency of business processes. Blockchain allows to open new opportunities in insurance, solve some of the problems listed and significantly modernize the industry:•...…Why it is necessary and usefulThe insurance industry is a huge market. In the United States, in 2019, the volume of paid insurance premiums amounted to a trillion dollars. However, despite such volumes, the industry is experiencing great difficulties, because of which insurance companies are losing more than $100 billion every year. Most of the problems are fraud, poor-quality data or lack thereof, as well as the general inefficiency of business processes. Blockchain allows to open new opportunities in insurance, solve some of the problems listed and significantly modernize the industry:•...WW…

— Author: Firas GHRIBIIf you are interested in my writings or for a collaboration/opportunity or a private feedback or you want to ask me something, please don’t hesitate to contact me. : firas.ghribi@outlook.com | | | You may disagree with me, and 98% of readers will. But first, just forget about these countries : Russia, Iran, Cuba, Venezuela and all non democratic countries/Non liberal Economies. Here is why? :In short : These stated countries are censoring information and try to minimize the impact of their economic downturn. their news are not relevant to built a true insight of the...…— Author: Firas GHRIBIIf you are interested in my writings or for a collaboration/opportunity or a private feedback or you want to ask me something, please don’t hesitate to contact me. : firas.ghribi@outlook.com | | | You may disagree with me, and 98% of readers will. But first, just forget about these countries : Russia, Iran, Cuba, Venezuela and all non democratic countries/Non liberal Economies. Here is why? :In short : These stated countries are censoring information and try to minimize the impact of their economic downturn. their news are not relevant to built a true insight of the...WW…

Four years ago I wanted to know everything I could about him. Where his money came from, where he came from, what he was like as a boss, what he’s like as a person, hell, I ever read Stormy Daniels book to try and find out what he was like in bed! Of course I read and pre-election bios like but quickly moved into the deep analysis with books like, and gobbled up books like, the day they came out.At first it was out of fear. I was scared of what Trump would do to the country. The second half of November 2016 I was sure nuclear war was on the immediate horizon. The obviousness of his...…Four years ago I wanted to know everything I could about him. Where his money came from, where he came from, what he was like as a boss, what he’s like as a person, hell, I ever read Stormy Daniels book to try and find out what he was like in bed! Of course I read and pre-election bios like but quickly moved into the deep analysis with books like, and gobbled up books like, the day they came out.At first it was out of fear. I was scared of what Trump would do to the country. The second half of November 2016 I was sure nuclear war was on the immediate horizon. The obviousness of his...WW…

TLDR: Thousands of MAGA accounts are engaging in coordinated inauthentic activity, churning out hundreds of millions of retweets of & other conservative accountsThe New York Times recently on Facebook, Twitter and YouTube allowing President Trump to disseminate “statements about unproven coronavirus treatments” — violating each platform’s respective Terms of Service (ToS) in the process.Despite Big Tech making very aggressive public statements (re: mitigating against platform manipulation), they aren’t taking down misinformation that is being spread by Donald Trump.Specific to Twitter, this...…TLDR: Thousands of MAGA accounts are engaging in coordinated inauthentic activity, churning out hundreds of millions of retweets of & other conservative accountsThe New York Times recently on Facebook, Twitter and YouTube allowing President Trump to disseminate “statements about unproven coronavirus treatments” — violating each platform’s respective Terms of Service (ToS) in the process.Despite Big Tech making very aggressive public statements (re: mitigating against platform manipulation), they aren’t taking down misinformation that is being spread by Donald Trump.Specific to Twitter, this...WW…

In recent years I’ve been a bit of a hermit… going down the rabbit holes of the internet. Between classes, while finishing my degree, on my breaks while managing a local gym, and of course in the wee hours of the night in my moments of insomnia.Fears of the toppling of the ‘American Empire’ seem to be at all-time-highs nowadays. Those of which are grounded in facts, data and are not based in conspiracy theories — I am not at all surprised by these fears. The things that I’ve stumbled across, and the dots that I’ve been connecting are disappointing, daunting and most of all; infuriating....…In recent years I’ve been a bit of a hermit… going down the rabbit holes of the internet. Between classes, while finishing my degree, on my breaks while managing a local gym, and of course in the wee hours of the night in my moments of insomnia.Fears of the toppling of the ‘American Empire’ seem to be at all-time-highs nowadays. Those of which are grounded in facts, data and are not based in conspiracy theories — I am not at all surprised by these fears. The things that I’ve stumbled across, and the dots that I’ve been connecting are disappointing, daunting and most of all; infuriating....WW…

Throughout the Sound in March and April, Pacific herring were spawning in large numbers. In Quilcene Bay and Dabob Bay, in Port Orchard and Port Madison, in Henderson Bay, and near West Seattle, and possibly in Discovery Bay, Holmes Harbor, and elsewhere. There’s uncertainty about the precise extent and the size of the spawning due to stay-at-home restrictions limiting observation and measurement, but it’s clear that this has been a big year for herring. Pacific herring and other forage fish play an important role in the food web of the Salish Sea, and their .“Our Sound-wide total for 2019...…Throughout the Sound in March and April, Pacific herring were spawning in large numbers. In Quilcene Bay and Dabob Bay, in Port Orchard and Port Madison, in Henderson Bay, and near West Seattle, and possibly in Discovery Bay, Holmes Harbor, and elsewhere. There’s uncertainty about the precise extent and the size of the spawning due to stay-at-home restrictions limiting observation and measurement, but it’s clear that this has been a big year for herring. Pacific herring and other forage fish play an important role in the food web of the Salish Sea, and their .“Our Sound-wide total for 2019...WW…

This post written by Jon Klein, co-founder at I have a Master’s degree in Complex Adaptive Systems. And when I tell people that, there’s typically a short pause, followed by the obvious question: “What are complex adaptive systems?”. And so I normally go on a long-winded spiel about biological systems or social interactions or turtles on lily pads or traffic jams and usually this helps people kind-of-sort-of understand what complex systems are all about.Over the past 3 months though, explaining complex adaptive systems has become a lot easier: you know that global pandemic that we’re all...…This post written by Jon Klein, co-founder at I have a Master’s degree in Complex Adaptive Systems. And when I tell people that, there’s typically a short pause, followed by the obvious question: “What are complex adaptive systems?”. And so I normally go on a long-winded spiel about biological systems or social interactions or turtles on lily pads or traffic jams and usually this helps people kind-of-sort-of understand what complex systems are all about.Over the past 3 months though, explaining complex adaptive systems has become a lot easier: you know that global pandemic that we’re all...WW…

The Complications of Big Philanthropy in a Small Cityby Michael Mason“It is a truism to say that Tulsa is the most American of American Cities. All the forces that have gone into the making of the Republic have been intensified here.” —Angie Debo, Tulsa: From Creek Town to Oil Capitalpril 20, 2020, was an unimaginable day for most Tulsans. An essential economic engine had suddenly been thrown into reverse. For the first time in history, the price of oil plummeted so far that futures went negative. Though Tulsa is no longer the oil capital it once was, the oil and gas industry still provides...…The Complications of Big Philanthropy in a Small Cityby Michael Mason“It is a truism to say that Tulsa is the most American of American Cities. All the forces that have gone into the making of the Republic have been intensified here.” —Angie Debo, Tulsa: From Creek Town to Oil Capitalpril 20, 2020, was an unimaginable day for most Tulsans. An essential economic engine had suddenly been thrown into reverse. For the first time in history, the price of oil plummeted so far that futures went negative. Though Tulsa is no longer the oil capital it once was, the oil and gas industry still provides...WW…

Artificial Intelligence (AI) is by no means a novel concept. From HAL 9000 in 2001: A Space Odyssey to iconic Star Wars droids like RD2D and the adorable BB-8, humans have long been dreaming of harnessing the power of AI to fuel technological revolutions.More recently, AI has been making waves in banking and finance, with widespread applications across different fields. We sat down with Sanjay Uppal, Founder and CEO of , who has been working with the DBS Institutional Banking and team on bringing AI technologies into the bank. He shares insights into the potential of AI-powered intelligent...…Artificial Intelligence (AI) is by no means a novel concept. From HAL 9000 in 2001: A Space Odyssey to iconic Star Wars droids like RD2D and the adorable BB-8, humans have long been dreaming of harnessing the power of AI to fuel technological revolutions.More recently, AI has been making waves in banking and finance, with widespread applications across different fields. We sat down with Sanjay Uppal, Founder and CEO of , who has been working with the DBS Institutional Banking and team on bringing AI technologies into the bank. He shares insights into the potential of AI-powered intelligent...WW…

Disclaimer: code and demo at the end of the article.This started out as a challenge. I wanted with a of mine to see if it was possible to build something from scratch and push it to production. In 3 weeks. This is our story. for more posts like this.In this post, we’ll go through the necessary steps to build and deploy a machine learning application. This starts from data collection to deployment and the journey, as you’ll see it, is exciting and fun 😀.Before we begin, let’s have a look at the app we’ll be building:As you see, this web app allows a user to evaluate random brands by writing...…Disclaimer: code and demo at the end of the article.This started out as a challenge. I wanted with a of mine to see if it was possible to build something from scratch and push it to production. In 3 weeks. This is our story. for more posts like this.In this post, we’ll go through the necessary steps to build and deploy a machine learning application. This starts from data collection to deployment and the journey, as you’ll see it, is exciting and fun 😀.Before we begin, let’s have a look at the app we’ll be building:As you see, this web app allows a user to evaluate random brands by writing...WW…

is an amazing financial instrument. Never before in history has a store of value, or currency, had what Bitcoin can and does provide. Despite consistent and massive movements upward, few traders capture the profits that Bitcoin offers. The obvious question is “why”? The answer, for those of you in a hurry, points to two factors, and .Regardless of instrument or market, the average trader has perennially been over forty years old, and almost exclusively male (Cis!). This “average trader” did not come into existence accidentally. Economic pressures, Darwinian culling of unskilled traders, and...…is an amazing financial instrument. Never before in history has a store of value, or currency, had what Bitcoin can and does provide. Despite consistent and massive movements upward, few traders capture the profits that Bitcoin offers. The obvious question is “why”? The answer, for those of you in a hurry, points to two factors, and .Regardless of instrument or market, the average trader has perennially been over forty years old, and almost exclusively male (Cis!). This “average trader” did not come into existence accidentally. Economic pressures, Darwinian culling of unskilled traders, and...WW…