AMI Images/SPL Phages (green) attack a bacterium (orange). Researchers are hoping to use engineered versions of these viruses to fight antibiotic resistance.Genetically modified viruses that cause bacteria to kill themselves could be the next step in . Several companies have engineered such viruses, called bacteriophages, to use the CRISPR gene-editing system to kill specific bacteria, according to a presentation at the CRISPR 2017 conference in Big Sky, Montana, last week. These companies could begin clinical trials of therapies as soon as next year. Initial tests have saved mice from...…AMI Images/SPL Phages (green) attack a bacterium (orange). Researchers are hoping to use engineered versions of these viruses to fight antibiotic resistance.Genetically modified viruses that cause bacteria to kill themselves could be the next step in . Several companies have engineered such viruses, called bacteriophages, to use the CRISPR gene-editing system to kill specific bacteria, according to a presentation at the CRISPR 2017 conference in Big Sky, Montana, last week. These companies could begin clinical trials of therapies as soon as next year. Initial tests have saved mice from...WW…

In a one-of-a-kind race, DNA motors have achieved some of the fastest speeds and longest distances ever travelled by nanometre-scale machines.The track: a standard glass slide covered with RNA. For the motors, Yonggang Ke, Khalid Salaita and their colleagues at Emory University in Atlanta, Georgia, folded a very long strand of DNA back on itself 16 times to create a 3D beam. The researchers attached 36 ‘legs’ — short RNA strands that could bind the RNA on the track — to each of the beam’s 4 long faces.After the DNA devices were placed on the track, the legs on the bottom face found their...…In a one-of-a-kind race, DNA motors have achieved some of the fastest speeds and longest distances ever travelled by nanometre-scale machines.The track: a standard glass slide covered with RNA. For the motors, Yonggang Ke, Khalid Salaita and their colleagues at Emory University in Atlanta, Georgia, folded a very long strand of DNA back on itself 16 times to create a 3D beam. The researchers attached 36 ‘legs’ — short RNA strands that could bind the RNA on the track — to each of the beam’s 4 long faces.After the DNA devices were placed on the track, the legs on the bottom face found their...WW…

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtainthe best experience, we recommend you use a more up to date browser (or turn off compatibility mode inInternet Explorer). In the meantime, to ensure continued support, we are displaying the site without stylesand JavaScript.A Nature Research JournalGlobal insights into cellular organization and genome function require comprehensive understanding of the interactome networks that mediate genotype–phenotype relationships,. Here we present a human ‘all-by-all’ reference interactome map of...…Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtainthe best experience, we recommend you use a more up to date browser (or turn off compatibility mode inInternet Explorer). In the meantime, to ensure continued support, we are displaying the site without stylesand JavaScript.A Nature Research JournalGlobal insights into cellular organization and genome function require comprehensive understanding of the interactome networks that mediate genotype–phenotype relationships,. Here we present a human ‘all-by-all’ reference interactome map of...WW…

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtainthe best experience, we recommend you use a more up to date browser (or turn off compatibility mode inInternet Explorer). In the meantime, to ensure continued support, we are displaying the site without stylesand JavaScript.A Nature Research JournalUltra-hot giant exoplanets receive thousands of times Earth’s insolation1,2. Their high-temperature atmospheres (greater than 2,000 kelvin) are ideal laboratories for studying extreme planetary climates and chemistry3–5. Daysides are...…Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtainthe best experience, we recommend you use a more up to date browser (or turn off compatibility mode inInternet Explorer). In the meantime, to ensure continued support, we are displaying the site without stylesand JavaScript.A Nature Research JournalUltra-hot giant exoplanets receive thousands of times Earth’s insolation1,2. Their high-temperature atmospheres (greater than 2,000 kelvin) are ideal laboratories for studying extreme planetary climates and chemistry3–5. Daysides are...WW…

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtainthe best experience, we recommend you use a more up to date browser (or turn off compatibility mode inInternet Explorer). In the meantime, to ensure continued support, we are displaying the site without stylesand JavaScript.A Nature Research JournalMost scholarship on the closely-watched case of genetically modified Bacillus thuringiensis (Bt) cotton in India has focused on short-term impacts and has also ignored other major changes in India’s cotton agriculture. This Perspective...…Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtainthe best experience, we recommend you use a more up to date browser (or turn off compatibility mode inInternet Explorer). In the meantime, to ensure continued support, we are displaying the site without stylesand JavaScript.A Nature Research JournalMost scholarship on the closely-watched case of genetically modified Bacillus thuringiensis (Bt) cotton in India has focused on short-term impacts and has also ignored other major changes in India’s cotton agriculture. This Perspective...WW…

An open-resource literature hub known as LitCovid curates the most comprehensive collection of international research papers so far on the new coronavirus disease COVID-19 (see ). Developed with the support of the US National Institutes of Health’s intramural research programme, LitCovid is updated daily with newly published articles. The aim is to provide timely insight from the scientific literature into the biology of the virus and the diagnosis and management of those who have been infected.LitCovid has a more sophisticated search function than existing resources. It identifies roughly...…An open-resource literature hub known as LitCovid curates the most comprehensive collection of international research papers so far on the new coronavirus disease COVID-19 (see ). Developed with the support of the US National Institutes of Health’s intramural research programme, LitCovid is updated daily with newly published articles. The aim is to provide timely insight from the scientific literature into the biology of the virus and the diagnosis and management of those who have been infected.LitCovid has a more sophisticated search function than existing resources. It identifies roughly...WW…

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtainthe best experience, we recommend you use a more up to date browser (or turn off compatibility mode inInternet Explorer). In the meantime, to ensure continued support, we are displaying the site without stylesand JavaScript.Springer Nature is making SARS-CoV-2 and COVID-19 research free.||A Nature Research JournalPlasma phosphorylated tau181 (P-tau181) might be increased in Alzheimer’s disease (AD), but its usefulness for differential diagnosis and prognosis is unclear. We studied...…Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtainthe best experience, we recommend you use a more up to date browser (or turn off compatibility mode inInternet Explorer). In the meantime, to ensure continued support, we are displaying the site without stylesand JavaScript.Springer Nature is making SARS-CoV-2 and COVID-19 research free.||A Nature Research JournalPlasma phosphorylated tau181 (P-tau181) might be increased in Alzheimer’s disease (AD), but its usefulness for differential diagnosis and prognosis is unclear. We studied...WW…

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtainthe best experience, we recommend you use a more up to date browser (or turn off compatibility mode inInternet Explorer). In the meantime, to ensure continued support, we are displaying the site without stylesand JavaScript.A Nature Research JournalPathological aggregates of tau proteins accumulate in the brains of neurodegenerative tauopathies including Alzheimer’s disease and frontotemporal lobar degeneration (FTLD-tau). Although immunotherapies of these disorders against tau are...…Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtainthe best experience, we recommend you use a more up to date browser (or turn off compatibility mode inInternet Explorer). In the meantime, to ensure continued support, we are displaying the site without stylesand JavaScript.A Nature Research JournalPathological aggregates of tau proteins accumulate in the brains of neurodegenerative tauopathies including Alzheimer’s disease and frontotemporal lobar degeneration (FTLD-tau). Although immunotherapies of these disorders against tau are...WW…

Efforts to curb greenhouse gas-emissions and the impacts of global warming will fall significantly short without drastic changes in global land use, agriculture and human diets, leading researchers warn in a high-level report commissioned by the United Nations. The special report on climate and land by the Intergovernmental Panel on Climate Change (IPCC) describes plant-based diets as a major opportunity for mitigating and adapting to climate change ― and includes a policy recommendation to reduce meat consumption.On 8 August, the IPCC released a summary of the report, which is designed to...…Efforts to curb greenhouse gas-emissions and the impacts of global warming will fall significantly short without drastic changes in global land use, agriculture and human diets, leading researchers warn in a high-level report commissioned by the United Nations. The special report on climate and land by the Intergovernmental Panel on Climate Change (IPCC) describes plant-based diets as a major opportunity for mitigating and adapting to climate change ― and includes a policy recommendation to reduce meat consumption.On 8 August, the IPCC released a summary of the report, which is designed to...WW…